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DIYgenomics is a non-profit research organization making
personal genomic information useful to individuals.
Information is not intended is to replace advice from health professionals.
Personalized Genomics Apps DIYgenomics provides apps on the web and mobile platforms, some of which include the ability to privately upload 23andMe data for review. The apps feature health risk (a side-by-side comparison of markers reviewed by consumer genomic companies for the top 20 health conditions), drug response (identifying markers associated with metabolism and side effects for 250 drugs), and athletic performance capability. The DIYgenomics Health Risk Web Application provides a side-by-side comparison of consumer genomic services (23andme, deCODEme, Navigenics) by locus, gene, and variant for 20 conditions (Alzheimer's disease, diabetes, cancers, heart disease, etc.). The DIYgenomics Drug Reponse Web Application provides a side-by-side comparison of locus, gene and variant information for 200 drugs (clopidogrel (Plavix), morphine, sildenafil (Viagra), warfarin, etc.). If a variant is reviewed, the underlying research references cited are posted in the table below. 'Sample data' is information from one person's 23andme file; not all the variants reviewed for drugs are genotyped currently by 23andme. One or two variant mutations could be interpreted as the usual dose of the drug possibly being 'less efficacious.' Green is the normal genotype, red is the mutation. * means that the FDA has validated genomic biomarkers for this drug. 'Rank' is a composite score assigned to the variant by DIYgenomics per journal ranking, number of cases and controls, p-value, and odds ratio (rank assessment methodology). The DIYgenomics Athletic Performance Web Application provides a list of the genes and variants that research studies link to thirteen different categories of athletic performance including strength, endurance, muscle development, lung capacity, and recovery. |
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